Dr. Rustem R. Zairov_CAFM 2023

Biography
Dr. Rustem R. Zairov Kazan (Volga region) Federal University, Russia
Title: Luminescent thermo- and chemosensing using Ln(III) chelates nanoparticles
Abstract: Luminescent lanthanide complexes have long attracting researchers due to their excellent optical properties. They are widely used as building blocks for luminescent nanomaterials for application in biomedical analysis, medical diagnosis, and cell imaging[1, 2]. Long luminescence lifetimes, sharp characteristic emission bands, and large Stoke’s shifts allow getting rid of biological background autofluorescence, which is of great importance when biomedical experiments are conducted. The wide applicability of lanthanide complexes in fluorescent sensing of residual amounts of drugs, including antibiotics, in water or biological fluids is well-known[3, 4]. In this regard, the synthesis of new lanthanide complexes, where ligand-to-metal energy transfer is enough for sensitizing lanthanide-centered luminescence, and ligand-metal coordination bonds are tight enough for the safe conversion of the complexes into water-dispersible nanomaterial with high lanthanide-centered luminescence is a challenging scientific task. The applicability of the developed aqueous colloids as nanosensors will be demonstrated by their luminescent reply on ceftriaxone, which is the third generation of cephalosporin antibiotic widely applied in treating of such socially relevant bacterial infections as meningitis, pneumonia and many others as well as fluoroquinolones antibiotics, glyphosate and temperature [5-7]. Acknowledgement. The authors thank the Russian Science Foundation (grant 22-13-00010) for financial support. RZ and AD thank the Kazan Federal University Strategic Academic Leadership Program (PRIORITY-2030) for support. References 1. S. N. Podyachev, R. R. Zairov and A. R. Mustafina. Molecules 2021, 26(5), 1214. 10.3390/molecules26051214. 2. R. Zairov, et al. Scientific Reports. 10, Art.num. 20541 (2020). 10.1038/s41598-020-77512-1. 3. R. Zairov, et al. Nanomaterials 2023, 13(3), 438; https://doi.org/10.3390/nano13030438. 4. N. Davydov, et al. Analytica Chimica Acta, 2013, 784, pp. 65-71. 10.1016/j.aca.2013.04.054. 5. R. R. Zairov, et al. Colloids and Surfaces B: Biointerfaces, 217(2022), 112664. 10.1016/j.colsurfb.2022.112664 6. R. R. Zairov, et al. Sensors & Actuators: B. Chemical, 350 (2022) 130845. 10.1016/j.snb.2021.130845. 10.1016/j.snb.2021.130845. 7. R. R. Zairov, et al. Nanomaterials 2021, 11, 3080. https://doi.org/10.3390/nano11113080.

Biography

Dr. Rustem R. Zairov
Kazan (Volga region) Federal University, Russia

Title: Luminescent thermo- and chemosensing using Ln(III) chelates nanoparticles

Abstract:

Luminescent lanthanide complexes have long attracting researchers due to their excellent optical properties. They are widely used as building blocks for luminescent nanomaterials for application in biomedical analysis, medical diagnosis, and cell imaging[1, 2]. Long luminescence lifetimes, sharp characteristic emission bands, and large Stoke’s shifts allow getting rid of biological background autofluorescence, which is of great importance when biomedical experiments are conducted.

The wide applicability of lanthanide complexes in fluorescent sensing of residual amounts of drugs, including antibiotics, in water or biological fluids is well-known[3, 4]. In this regard, the synthesis of new lanthanide complexes, where ligand-to-metal energy transfer is enough for sensitizing lanthanide-centered luminescence, and ligand-metal coordination bonds are tight enough for the safe conversion of the complexes into water-dispersible nanomaterial with high lanthanide-centered luminescence is a challenging scientific task.

The applicability of the developed aqueous colloids as nanosensors will be demonstrated by their luminescent reply on ceftriaxone, which is the third generation of cephalosporin antibiotic widely applied in treating of such socially relevant bacterial infections as meningitis, pneumonia and many others as well as fluoroquinolones antibiotics, glyphosate and temperature [5-7].

Acknowledgement. The authors thank the Russian Science Foundation (grant 22-13-00010) for financial support. RZ and AD thank the Kazan Federal University Strategic Academic Leadership Program (PRIORITY-2030) for support.

References

1. S. N. Podyachev, R. R. Zairov and A. R. Mustafina. Molecules 2021, 26(5), 1214. 10.3390/molecules26051214.

2. R. Zairov, et al. Scientific Reports. 10, Art.num. 20541 (2020). 10.1038/s41598-020-77512-1.

3. R. Zairov, et al. Nanomaterials 2023, 13(3), 438; https://doi.org/10.3390/nano13030438.

4. N. Davydov, et al. Analytica Chimica Acta, 2013, 784, pp. 65-71. 10.1016/j.aca.2013.04.054.

5. R. R. Zairov, et al. Colloids and Surfaces B: Biointerfaces, 217(2022), 112664. 10.1016/j.colsurfb.2022.112664

6. R. R. Zairov, et al. Sensors & Actuators: B. Chemical, 350 (2022) 130845. 10.1016/j.snb.2021.130845. 10.1016/j.snb.2021.130845.

7. R. R. Zairov, et al. Nanomaterials 2021, 11, 3080. https://doi.org/10.3390/nano11113080.